H2-receptor blockers,

H2 antagonists (ATC A 02-BA) - a g roup of drugs introduced into therapeutics in 1972, whose mechani sm of action is based on blocking the H2 receptor histaminergiczn ego so is blocked histamine-dependent mechanisms to enhance the p roduction of gastric juice and its main component or hydrochloric acid. Depending on the substance, in varying degrees, blocking the rest of hydrochloric acid secretion, as induced by the stimulus of food, histamine, or pentagastrin. These medicines are used to treat ulcers, Zollinger-Ellison syndrome, gastro-esophageal reflux and dyspepsia, but are increasingly being replaced by the use of proton pump blockers. Some of the H2-receptor antagonists used in hospitals: Currently, drugs in this group have become less important due to the discovery of proton pump inhibitors, which show a stronger inhibitory effect of acid secretion.

Tagi: antagonists blocking blocked to its the These treat